Get started
Weight LossLabs, a plan and Lipo-Bfrom $119 per orderMenopauseHormone creams and estradiolfrom $99 per orderTestosteroneLabs-first testingComing soonSexual HealthDesire, comfort and confidencefrom $39 per orderHairThinning hair, women and menfrom $29 per orderSkinCopper peptide skincarefrom $289 per orderLongevityNAD+, glutathione, sermorelinfrom $119 per orderRecoveryBPC-157 and recovery peptidesComing soonLabsPartner lab panelsComing soon
For women For men
Not sure where to start? A five-minute assessment points you to the right care.See all treatments Take the free assessment
LovCura vaginal estradiol cream on pale stone

Illustrative photo. Your medication ships from a licensed pharmacy, and its packaging may look different.

Menopause · Local, low dose

Vaginal estradiol cream

2 mg/mL, 30 mL

Compounded, not FDA-approved

A low-dose topical estradiol cream for localized menopausal symptom relief.

Prescription onlySee all prices
One-time price, per order$99
Start my order

Each order adds $39 shipping and a $39 consultation fee. You pay the consultation fee at checkout, then complete a short medical questionnaire. Your medication and shipping are charged after a licensed clinician approves your prescription. No membership needed. Payment does not guarantee a prescription. Not sure? Take the assessment

  • Licensed clinician review
  • Discreet delivery
  • Prescription only
What it is

What is Vaginal estradiol cream?

A low-dose topical estradiol cream applied vaginally, formulated for women experiencing localized menopausal symptoms rather than systemic hormone changes.

May help with

  • Vaginal dryness and discomfort
  • Painful intercourse related to hormonal decline
  • Urinary symptoms linked to vaginal tissue changes

Individual results vary. Your clinician tells you plainly what to expect for you.

How it works

How it works.

Applied directly to vaginal tissue, estradiol cream restores localized estrogen levels to support tissue health, elasticity, and moisture, with minimal systemic absorption compared to oral or transdermal hormone therapy. Your provider sets an application schedule based on your symptoms.

What to expect

  1. Weeks 2 to 4

    Improved comfort and moisture

  2. Month 2 and beyond

    Continued tissue health with regular use

Everyone responds differently. These are general check-in points, not promised results.

Quick answers

The short version.

Cost, prescriptions, FDA status and delivery for vaginal estradiol cream. Your clinician covers the rest with you.

All questions

Vaginal estradiol cream is $99 per order, a one-time price. Each order adds $39 shipping and a $39 consultation fee, paid at checkout. Medication and shipping are charged after your clinician approves your prescription. There is no membership or monthly fee.

Yes. Vaginal estradiol cream is prescription only. After checkout you complete a short medical questionnaire, then a licensed clinician reviews your health history and decides whether it is right for you. Payment does not guarantee a prescription.

No. Vaginal estradiol cream is compounded, meaning a licensed pharmacy prepares it for an individual patient’s prescription. Compounded medications are not FDA-approved, so the FDA does not review them for safety, effectiveness or quality before they are dispensed.

Vaginal estradiol cream may help with vaginal dryness and discomfort, painful intercourse related to hormonal decline and urinary symptoms linked to vaginal tissue changes. Individual results vary, and your clinician will tell you plainly what to expect.

If your clinician prescribes it, it ships from a licensed U.S. pharmacy in discreet packaging. Shipping is $39 per order.

Your treatment journey

Four steps. One team.

The same clear path for every LovCura treatment, with a licensed clinician at every step.

Step 01

Start your online evaluation

Tell us about your health history and goals.

Step 02

Get approved by a clinician

A licensed LovCura clinician reviews your evaluation, and your labs when they are needed.

Step 03

Receive your treatment at home

Approved treatments ship discreetly to your door.

Step 04

Start with guidance

Begin your plan with ongoing support from your care team.

Safety

Important safety information

This is not the full list. Your clinician reviews all risks with you, and full information comes with every prescription. Full safety information

  • Vaginal estradiol. Report any unusual vaginal bleeding to your clinician.
  • Hormone therapy is not right for everyone. Your clinician reviews your personal and family history, including breast or uterine cancer, blood clots, stroke, heart disease and liver disease.
  • Compounded medications are not FDA-approved. The FDA does not verify their safety, effectiveness or quality.
  • Tell your clinician about every medication and supplement you take and every health condition you have.
Keep exploring

More in menopause

Cream + capsules

Estradiol + testosterone cream, with progesterone

cream (45 mL) and nightly capsules (90)
Compounded, not FDA-approved

A combination hormone regimen pairing a topical estradiol/testosterone cream with oral progesterone.

One-time price, per order$439
Cream

Testosterone cream

low dose, 1 or 2 mg/mL, 45 mL
Compounded, not FDA-approvedOff-label

A topical testosterone cream for patients whose labs indicate testosterone support alone.

One-time price, per order$199
All menopause care

Not sure this is the one?

Take the free five-minute assessment. A licensed clinician reviews your answers and recommends what fits.

Start free assessment